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Diabetes and Substance Use (Tobacco & Alcohol)
Tobacco Use and Diabetes
- Tobacco use, both smoked and smokeless, significantly increases the risk of type 2 diabetes by 30–40%
- Causes insulin resistance, chronic inflammation, and oxidative stress and endothelial dysfunction, worsening glycemic control and accelerating vascular complications (Sakthisankaran et al., 2024; Marbaniang et al., 2021).
- Worsens glycaemic control and accelerates complications
- Smokers have a 30–40% higher risk of developing type 2 diabetes compared to non-smokers (Mishra et al., 2022).
- Poor glucose control worsens stress, irritability, and fatigue


